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January 18, 2024

Compliance with Ethics Guidelines All four trials were conducted in accordance with the International Conference on Harmonisation Good Clinical Practice guidelines and the Declaration of Helsinki

187 In a randomized controlled trial that included 44 subjects with NAFLD, taking 1,000 mg ginger twice daily for 12 weeks lowered ALT and GGT levels, inflammatory cytokine levels, insulin resistance, and ultrasound-assessed liver fat, but did not affect AST levels or fibrosis relative to placebo

If combined GI symptoms become severe or persistent, notify your prescribing provider immediatelythey may adjust timing protocols, reduce doxycycline dose frequency, or recommend short-term anti-nausea medications to bridge the adjustment period

Note: GLP-1 receptor agonists such as semaglutide, liraglutide, and tirzepatide are a distinct class of pharmacological agents not lipotropic compounds